The presence of autoantibodies is associated with improved overall survival in lung cancer patients

Objective Autoantibodies have been reported to be associated with cancers. As a biomarker, autoantibodies widely used in the early screening of lung cancer. However, correlation between and prognosis cancer patients is poorly understood, especially Asian population. This retrospective study investigated association presence outcomes Methods A total 264 diagnosed were tested for Henan Provincial People’s Hospital from January 2017 June 2022. The general clinical data these collected, after out those who met exclusion criteria, 151 finally included study. Cox proportional hazards model was analyze effect on Kaplan-Meier curve relationship overall survival Results Compared without autoantibodies, had an reduced risk death (HRs: 0.45, 95% CIs 0.27~0.77), independent gender, age, smoking history, pathological type, stage Additionally, found more significant by subgroup analysis male patients, younger small cell Furthermore, significantly longer time than autoantibodies. Conclusion indicator good cancer, providing new biomarker prognostic evaluation